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Digital CRISPR-based diagnostics for quantification of Candida auris and resistance mutations - Nature Biomedical Engineering
58+ min ago (1351+ words) WHO Fungal Priority Pathogens List to Guide Research, Development and Public Health Action (World Health Organization, 2022). Fisher, M. C. et al. Tackling the emerging threat of antifungal resistance to human health. Nat. Rev. Microbiol. 20, 557571 (2022). Antibiotic Resistance Threats in the United States 2019 (CDC,…...
A foundation model for continuous glucose monitoring data
1+ hour, 50+ min ago (1355+ words) Nature (2026)Cite this article Shilo, S. et al. 10 K: a large-scale prospective longitudinal study in Israel. Eur. J. Epidemiol. 36, 11871194 (2021). Reicher, L. et al. Deep phenotyping of healthdisease continuum in the Human Phenotype Project. Nat. Med. 31, 31913203 (2025). Nathan, D. M. et al. The effect of intensive treatment of…...
Pan-disease dimensions in the brain, eye and heart capture shared and specific heterogeneity - Nature Mental Health
1+ hour, 58+ min ago (130+ words) Nature Mental Health (2026)Cite this article only $6.58 per issue Wen, J. et al. Neuroimaging endophenotypes reveal underlying mechanisms and genetic factors contributing to progression and development of four brain disorders. Nat. Biomed. Eng. 9, 19201937 (2025). An article that presents our previous investigation into…...
Clinical outcomes of influenza in individuals aged ≤20 years before and after COVID-19: a national analysis of mortality and complications - Pediatric Research
7+ hour, 33+ min ago (1350+ words) The COVID-19 pandemic has altered the typical annual pattern of influenza. We aim to assess its impact on influenza outcomes, especially on mortality, cardiovascular, and non-cardiovascular complications. This study utilized discharge records from the National Inpatient Sample (NIS) for 2019 and…...
Procoagulant platelets: linking coagulation and thromboinflammation in cardiovascular disease - Nature Reviews Cardiology
8+ hour, 10+ min ago (1648+ words) Triggers of procoagulant activation include high shear stress rates and parallel stimulation of platelets by multiple agonists, leading to sustained rises in intracellular Ca2+ levels. Inhibition of procoagulant activity by specific targeting of the involved cellular machinery has shown efficacy in…...
Unravelling co-mutational patterns with prognostic implications in NPM1 mutated adult acute myeloid leukemia – a HARMONY study - Leukemia
8+ hour, 29+ min ago (1742+ words) Leukemia (2026)Cite this article Cytogenetic aberrations are uncommon in this AML subtype, where a normal karyotype has been reported in 80-88% of the patients [17,18,19,20,21]. Most of them do not seem to affect the risk stratification, with the exception of infrequent ( Hence,…...
Pleiotropic genes linking congenital hypogonadotropic hypogonadism and cleft lip/palate: evidence from a genomic CHH cohort study - European Journal of Human Genetics
11+ hour, 23+ min ago (1718+ words) European Journal of Human Genetics (2026)Cite this article Genomic DNA was extracted from blood samples of the 336 patients with CHH and their available relatives using standard protocols provided by the manufacturer. WES and WGS were performed using the Agilent SureSelect…...
Characteristics and developmental trajectory of clinical trials focused on tumor-infiltrating lymphocytes for cancer treatment - Cancer Gene Therapy
11+ hour, 31+ min ago (1802+ words) Cancer Gene Therapy (2026)Cite this article Miller KD, Nogueira L, Mariotto AB, Rowland JH, Yabroff KR, Alfano CM, et al. Cancer treatment and survivorship statistics, 2019. CA Cancer J Clin. 2019;69:36385. Luo N. Advances in Targeted Immunotherapy in Cancers. Int J Mol Sci....
tRNA m1A modification orchestrates STING translation in macrophages to enhance antitumor immunity and CAR-macrophage immunotherapy - Cellular & Molecular Immunology
12+ hour, 34+ min ago (1593+ words) Cellular & Molecular Immunology (2026)Cite this article Kloosterman DJ, Akkari L. Macrophages at the interface of the coevolving cancer ecosystem. Cell. 2023;186:162751. Cassetta L, Pollard JW. Targeting macrophages: therapeutic approaches in cancer. Nat Rev Drug Discov. 2018;17:887904. Snell LM, McGaha TL, Brooks DG. Type…...
Ferroptotic tumour cells inhibit dendritic cell maturation through GPX4 release - Nature Reviews Immunology
12+ hour, 34+ min ago (349+ words) Ferroptotic tumour cells inhibit dendritic cell maturation through GPX4 release'Nature Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date…...