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Cannabis use alters how the human brain processes nicotine, new research suggests
1+ week, 8+ hour ago (934+ words) Cannabis and tobacco are frequently used together, and co-use is rising as legal cannabis markets expand and product varieties increase. Cannabis is a psychoactive plant containing compounds like delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). Nicotine is the highly addictive chemical…...
First human trial of psilocin since the 1960s reveals better tolerability than psilocybin
1+ week, 2+ day ago (679+ words) Recent research suggests that consuming psilocin, the active compound in “magic” mushrooms, might cause fewer side effects than taking psilocybin. The study also explored taking the drug under the tongue, finding it well tolerated though less intense at the tested…...
Psilocybin therapy shows strong potential for treating cocaine addiction
1+ week, 5+ day ago (292+ words) Cocaine use disorder is a chronic condition in which a person compulsively seeks and uses cocaine despite negative consequences to their health, finances, and personal life. Medical treatments for the disorder have long been lacking. For example, a 2021 review evaluated…...
Psychedelics may cause slight personality changes, but other factors play a big role
1+ week, 6+ day ago (247+ words) German university students who tried a psychedelic for the first time showed small relative increases in Openness and decreases in Conscientiousness over one year, according to a study published in npj Mental Health Research. The differences became less certain after…...
Researchers discover preventative immune benefits of a little-known psychedelic compound
2+ week, 8+ hour ago (419+ words) A small study in mice suggests that administering a psychedelic compound before an immune system challenge can prevent brain inflammation and associated behavioral changes. The findings, published in the journal BMC Neuroscience, hint that these drugs might prime the nervous…...
Psilocybin reverses depressive behaviors and restores brain cell growth in stressed rats
2+ week, 2+ day ago (808+ words) Two doses of the psychedelic compound psilocybin can reverse signs of depression and anxiety in rats exposed to chronic stress. The substance appears to work by encouraging the growth of new brain cells and normalizing stress hormone levels. The research…...
Medicinal mushroom supplements linked to a sudden relapse of psychosis in new case report
4+ week, 1+ day ago (627+ words) PsyPost...