1+ hour, 8+ min ago   (648+ words) Previous studies showed that mice lacking the DNA repair protein OGG1 develop weaker muscles. In a new study published in the Journal of Biological Chemistry, researchers found that increasing OGG1 had the opposite effect: mice with more OGG1 ran longer and built endurance…...

1+ week, 1+ day ago   (266+ words) Viruses must copy their DNA inside infected cells, often using specialized proteins that help them replicate faster than the host. One class of these proteins, called single-stranded DNA annealing proteins or SSAPs, is a common virus favorite to expedite viral…...

1+ week, 6+ day ago   (305+ words) Cells rely on phosphorylation signaling pathways, wherein proteins play a game of telephone and pass along a phosphate modification, to control processes such as growth. It is, therefore, no surprise that cancer cells frequently hijack these pathways to promote uncontrolled,…...

2+ week, 33+ min ago   (1279+ words) “Atherosclerotic cardiovascular disease is a well-served disease right?” Ben Oakes, the CEO of Scribe Therapeutics asked. “There are dozens of drugs for it, so why do we need another one?” There are indeed many drugs for the prevention of atherosclerosis,…...

2+ week, 5+ day ago   (525+ words) Global health estimates indicate that GAS causes 500 million infections worldwide each year, yet no vaccine exists. Although the bacteria use multiple strategies to evade the immune system, researchers still know little about how the body coordinates its defenses over time…...

3+ week, 23+ hour ago   (222+ words) Become a member to receive the print edition four times a year and the digital edition monthly. Jeyashree Alagarsamy is a freelance scientific writer and experienced researcher with experience in atherosclerosis, lipid metabolism and neuroscience. She is dedicated to educational…...

4+ week, 1+ day ago   (243+ words) Become a member to receive the print edition four times a year and the digital edition monthly. Jeyashree Alagarsamy is a freelance scientific writer and experienced researcher with experience in atherosclerosis, lipid metabolism and neuroscience. She is dedicated to educational…...

1+ mon, 4+ day ago   (924+ words) Emergency surgeons treating severe vascular injuries have limited options: extracting a healthy vein to reroute blood flow or using a plastic graft that has a higher risk of getting infected. A new bioengineered blood vessel offers a third option, creating…...

1+ mon, 5+ day ago   (242+ words) “The Pershing Square Sohn Cancer Prize will empower my lab to pursue a high-risk, high-reward direction that existing funding mechanisms are not designed to support,” Sabari said in a UTSW Medical Center press release. “If successful, this work will establish…...

1+ mon, 1+ week ago   (467+ words) With few effective treatment options available, researchers at the University of Michigan are using genetics to identify mechanisms underlying MASLD and potential therapeutic targets. A recent study published in the Journal of Lipid Research revealed that rare loss-of-function mutations in…...