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Drug Target Review
drugtargetreview. com > beige-fat-identified-as-potential-target-for-blood-pressure-drugs > 682410. article

Beige fat identified as potential target for blood pressure drugs | News

1+ mon, 1+ week ago  (22+ words) New research shows beige fat around blood vessels helps regulate blood pressure, offering potential pathways for future therapies to reduce cardiovascular risk....

Drug Target Review
drugtargetreview. com > molecular-switch-discovery-could-lead-to-new-bone-disease-treatments > 2135429. article

Molecular switch discovery could lead to new bone disease treatments

1+ hour, 13+ min ago  (522+ words) Mc Gill University scientists have identified a molecular switch that activates an alternative heat-producing pathway in brown fat, revealing how glycerol binding to the TNAP enzyme could lead to new treatments for various bone diseases. Scientists at Mc Gill University…...

Drug Target Review
drugtargetreview. com > two-antimicrobials-show-efficacy-against-drug-resistant-pneumonia-pathogen > 2135426. article

Two antimicrobials show efficacy against drug-resistant pneumonia pathogen

22+ hour, 31+ min ago  (424+ words) Researchers at Osaka Metropolitan University have found that two antimicrobial treatments may help to fight against severe cases of hemorrhagic pneumonia caused by the multidrug-resistant bacterium Stenotrophomonas maltophilia which poses a growing threat to immunocompromised patients. The bacterium, commonly referred…...

Drug Target Review
drugtargetreview. com > asgct-2026-annual-meeting-opens-in-boston-this-week > 2135418. article

ASGCT 2026 Annual Meeting Opens in Boston this week

23+ hour, 41+ min ago  (350+ words) The American Society of Gene & Cell Therapy's 2026 Annual Meeting opens in Boston on 11 May, bringing together thousands of researchers, clinicians and industry leaders for five days of scientific sessions and discussion. The global cell and gene therapy sector will gather…...

Drug Target Review
drugtargetreview. com > yap1-protein-found-to-drive-chemotherapy-resistance-in-small-cell-lung-cancer-after-treatment > 2135390. article

YAP1 protein found to drive chemotherapy resistance in small cell lung cancer after treatment

5+ day, 23+ hour ago  (429+ words) A new study reveals that YAP1 protein expression occurs specifically after chemotherapy in small cell lung cancer, enabling cancer cells to survive treatment and driving disease relapse." Researchers at The University of Texas MD Anderson Cancer Center have identified a key…...

Drug Target Review
drugtargetreview. com > dr-salman-tamaddon-jahromi > 429445. bio

Dr Salman Tamaddon-Jahromi | Contributor

4+ day, 21+ hour ago  (236+ words) Dr Salman Tamaddon-Jahromi was Neurodegeneration Experimental Lead in the Open Targets Validation Lab at the Wellcome Sanger Institute, where he generated robust experimental evidence to support therapeutic target validation in Alzheimer's and Parkinson's disease. He specialises in high-throughput CRISPR'Cas9 functional…...

Drug Target Review
drugtargetreview. com > new-framework-evaluates-ai-reliability-in-immune-system-prediction > 2135385. article

New framework evaluates AI reliability in immune system prediction

5+ day, 2+ hour ago  (581+ words) A new University of South Florida study examines how AI models predict immune system responses to antigens, offering a framework to evaluate computational tools used in immunotherapy and vaccine development. Artificial intelligence is now a huge tool for scientists in…...

Drug Target Review
drugtargetreview. com > novel-enzyme-inhibitors-target-key-weakness-in-malaria-parasite > 2135381. article

Novel enzyme inhibitors target key weakness in malaria parasite

5+ day, 23+ hour ago  (445+ words) Scientists in the UK have developed a new class of compounds that target a key enzyme used by the malaria parasite to survive. Malaria is a life-threatening disease caused by parasites transmitted through mosquito bites, leading to an estimated 282 million…...

Drug Target Review
drugtargetreview. com > bispecific-antibody-targets-wnt-co-receptors-for-diabetic-macular-oedema-treatment > 2135380. article

Bispecific antibody targets Wnt co-receptors for diabetic macular oedema treatment

6+ day, 2+ hour ago  (416+ words) Neuvasq Biotechnologies has presented preclinical findings at ARVO 2026 showing that multispecific antibodies targeting Wnt co-receptors Gpr124 and Lrp6 can restore blood-retina barrier function in retinal vascular disease models." Neuvasq Biotechnologies"has announced new preclinical data that could lead to new and improved…...

Drug Target Review
drugtargetreview. com > reports > organoids-and-organ-chips-improving-decision-making-in-early-drug-discovery > 2135241. article

Organoids and Organ Chips: Improving Decision-Making in Early Drug Discovery

6+ day, 16+ hour ago  (198+ words) Early drug discovery has no shortage of models, but predicting what will translate to patients remains difficult. This report examines how organoids, organ-on-chip systems and imaging technologies are used to measure drug response, analyse resistance mechanisms and assess how well…...