4+ day, 17+ hour ago  (395+ words) Autism Brain Net has released new survey results that reveal a major gap between public support for autism research and awareness of how that research is carried out. While most Americans recognize the importance of studying the autistic brain, far…...

4+ mon, 5+ day ago  (434+ words) A unique opportunity to observe deep brain activity in a person with obesity and loss of control eating provided new insight into how tirzepatide, sold as Mounjaro and Zepbound, interacts with the brain. Recordings showed that the medication reduced activity…...

10+ mon, 2+ week ago  (270+ words) Mutations accumulated in mitochondrial DNA associated with aging were earlier believed to cause aging by decreasing the energy-producing function (mitochondrial respiratory function). In this study, researchers demonstrated that mitochondrial respiratory function is not reduced even when wild-type mice accumulated the…...

2+ mon, 2+ week ago  (441+ words) Aging immune cells may be sabotaging the body from within. Researchers found that macrophages produce a protein that locks them into a chronic inflammatory state, making infections like sepsis more deadly in older adults. Turning off this signal reduced inflammation…...

5+ mon, 5+ day ago  (257+ words) In Alzheimer's disease, the most common cause of dementia, microglia (the brain's immune cells) play a double role. They can protect the brain by clearing harmful debris or, under certain conditions, contribute to damage and inflammation. How these cells behave…...

3+ mon, 2+ week ago  (643+ words) As people grow older, visible changes like gray hair and weaker muscles are only part of the story. Aging also affects the immune system. One major reason is that the stem cells responsible for producing blood and immune cells can…...

4+ mon, 3+ week ago  (427+ words) The significance of this discovery became clearer when a Japanese study on supercentenarians, meaning individuals who live well past 100, found that this same T helper cell subset was abundant in their immune systems. Prof. Monsonego now believes these cells may…...

3+ mon, 2+ week ago  (1020+ words) As people get older, the immune system often becomes less effective. Populations of T cells shrink, and the remaining cells may respond more slowly to germs. That slowdown can leave older adults more vulnerable to many kinds of infections. To…...

6+ day, 8+ hour ago  (433+ words) "Epigenetic alterations are underappreciated as a major route to developing and fueling the growth of cancer metastasis," says Andrew Feinberg, M. D. , Bloomberg Distinguished Professor in the Johns Hopkins University schools of medicine, engineering and public health. Feinberg and his colleagues previously…...

2+ mon, 1+ week ago  (523+ words) Scientists have built a detailed map showing how hundreds of possible mutations in a major cancer gene affect tumor growth. The research offers a clearer picture of how small genetic changes can lead to very different cancer behaviors. The work…...