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A simple supplement can improve survival in patients with a novel heart disease
9+ mon, 1+ week ago (412+ words) Heart transplant is a scary and serious surgery with a high cost, but for patients with heart failure it can be the only option for cure. Now, however, a multi-institutional research team has found that simply taking a supplement might be all that is needed for certain patients with heart failure to recover'no surgery needed. The research team found that tricaprin, a natural supplement, can improve long-term survival and recovery from heart failure in patients with triglyceride deposit cardiomyovasculopathy (TGCV). TGCV is a new type of heart disease; it results from an impaired ability of the heart and smooth muscle... Heart transplant is a scary and serious surgery with a high cost, but for patients with heart failure it can be the only option for cure. Now, however, a multi-institutional research team has found that simply taking a supplement might…...
‘He still features in my nightmares’: how a sinister psychiatrist put hundreds of women in deep, drug-induced comas
8+ mon, 1+ day ago (401+ words) In the 1960s, William Sargant used a combination of narcosis and ECT to "reprogram" troubled young women. Now his patients, including the actor Celia Imrie and the former model Linda Keith, are trying to piece together what happenedSNIPEvery day, thousands of commuters and tourists pass beneath the former hospital. Some might look up to admire the terracotta facade, with its ornate colonnades and glazed tile lettering, but few are aware of the medical horrors that took place in one small room on the top floor: the Sleep Room. It was here, on ward five, that female patients " they were... In the 1960s, William Sargant used a combination of narcosis and ECT to "reprogram" troubled young women. Now his patients, including the actor Celia Imrie and the former model Linda Keith, are trying to piece together what happened Every day, thousands of commuters…...
Most in-depth simulation of brain metabolism yet reveals new targets for future dementia treatments
7+ mon, 4+ week ago (416+ words) A new open-source model of brain metabolism'the most complex ever generated'has shown how altering key chemicals could restore aged cells to their youthful activity and resilience. The researchers have found that reducing blood glucose, as well as increasing blood ketone and lactate levels, could help restore metabolic function in aging brains. Potentially, these could all be achieved through lifestyle changes, including exercise and the food we eat. The findings come from the most comprehensive computer model of brain metabolism to date, which incorporates more than 16,800 biochemical interactions between proteins and chemicals across brain cells, supporting cells, and the blood.... A new open-source model of brain metabolism'the most complex ever generated'has shown how altering key chemicals could restore aged cells to their youthful activity and resilience. The researchers have found that reducing blood glucose, as well as increasing blood ketone and…...
Smoking, obesity and Chesterton’s fence
3+ mon, 1+ day ago (404+ words) The percentage of the U.S. population that smoked tobacco in 1975 was 40%. That figure has declined steadily in the intervening years, and today, only 11% of the population are smokers. Knowing what we do about tobacco's risk to health, we can confidently identify the decline in smokers as progress in the realm of public health. However, over the same period, the percentage of the U.S. population defined as obese has climbed from 12% of the U.S. population to 42%. Rarely, does one find a correlation as striking as the inverse correlation of -.98 between the smoking and obesity rates... The percentage of the U.S. population that smoked tobacco in 1975 was 40%. That figure has declined steadily in the intervening years, and today, only 11% of the population are smokers. Knowing what we do about tobacco's risk to health, we can confidently identify the decline in smokers as progress in the realm…...
Getting treatment for high blood pressure may reduce chances of developing dementia
7+ mon, 1+ week ago (410+ words) Reducing high blood pressure substantially lowers the risk of dementia and cognitive impairment without dementia, according to the results of a phase 3 clinical trial involving almost 34,000 patients. These findings highlight the potential importance of widespread adoption of more intensive blood pressure control among patients with hypertension to reduce the global disease burden of dementia. Research has found that people with untreated hypertension have a 42% greater risk of developing dementia in their lifetime than healthy study participants. Jiang He and colleagues tested the effectiveness of an intervention led by non-physician community health care providers (sometimes called "village doctors")... Reducing high blood pressure substantially lowers the risk of dementia and cognitive impairment without dementia, according to the results of a phase 3 clinical trial involving almost 34,000 patients. These findings highlight the potential importance of widespread adoption of more intensive blood pressure control among…...
Red light linked to lowered risk of blood clots
10+ mon, 2+ week ago (427+ words) Humans and mice exposed to long-wavelength red light had lower rates of blood clots that can cause heart attacks, lung damage and strokes, according to research led by surgeon-scientists. The team exposed mice to 12 hours of either red, blue or white light, followed by 12 hours of darkness, in a 72-hour cycle. They then looked for differences in blood clots between the groups. The mice exposed to red light had nearly five times fewer clots than the mice exposed to blue or white light. Activity, sleep, eating, weight and body temperature remained the same between the groups. The team... Humans and mice exposed to long-wavelength red light had lower rates of blood clots that can cause heart attacks, lung damage and strokes, according to research led by surgeon-scientists. The team exposed mice to 12 hours of either red, blue or white light,…...
Study confirms brief apnea risk after vaccination of hospitalized preemies
10+ mon, 2+ week ago (417+ words) Hospitalized premature infants who received recommended two-month vaccinations had an increased risk of a short episode of apnea, but no serious complications arose, according to a study. The study confirms previous findings linking apnea, which is a pause in breathing, to vaccinations among premature babies. The potential side effect had been observed in some previous studies and is among those already identified on package inserts for several childhood vaccines. This new study confirms the risk of apnea in the 48 hours following vaccination for hospitalized premature infants. Greenberg noted that hospitalized premature infants have weak immune systems that make them... Hospitalized premature infants who received recommended two-month vaccinations had an increased risk of a short episode of apnea, but no serious complications arose, according to a study. The study confirms previous findings linking apnea, which is a pause in breathing, to…...
Special gut bacterium could help cut sugar cravings
10+ mon, 1+ week ago (408+ words) Researchers have identified a gut bacterium that may be associated with reduced dietary sugar intake. The findings, which are based on analyses of humans and mice, could aid the development of therapies to manage obesity and metabolic diseases, such as type 2 diabetes. Animals are biologically hardwired to crave sugars, but unmanaged sugar preference can lead to high sugar intake, resulting in high blood glucose and increased risk of metabolic diseases. Previous research suggests that our cravings for different foods originate from signals sent to the brain from the gut, a key organ in transmitting dietary preferences. However, the regulation... Researchers have identified a gut bacterium that may be associated with reduced dietary sugar intake. The findings, which are based on analyses of humans and mice, could aid the development of therapies to manage obesity and metabolic diseases, such as type…...
Looking for other with experience with CLL (Chronic Lymphocytic Leukemia)
9+ mon, 2+ week ago (415+ words) I was diagnosed with CLL a couple of years ago after having it for at least five years. I went from doctor to doctor trying to figure out what was wrong, getting dismissed by many. I had a PET scan recently and got results that it has progressed. Uptake in my throat and bone marrow, which wasn't in the scan I had two years ago. I've been having trouble swallowing for 2 1/2 years now. I went on a chemo drug called Calquence for a year after I was first diagnosed. They then switched me to Brukinsa. I went off... I was diagnosed with CLL a couple of years ago after having it for at least five years. I went from doctor to doctor trying to figure out what was wrong, getting dismissed by many. I had a PET scan recently and…...
He graduated early to get gender-affirming surgery before college. Then his hospital cut him off.
2+ mon, 4+ week ago (418+ words) Months before his first class at Carlow University, Lee, a 17-year-old in Pennsylvania, found himself without a provider. On a summer day, Lee sat waiting in a doctor's office, playing GamePigeon on his phone, telling family stories with his mom and deciding where to get dinner. It seemed like an ordinary afternoon, yet the reason for Lee's appointment was far from ordinary. Lee, 17, was there because the UPMC health system, headquartered in Pittsburgh, had cut off the gender-affirming care he'd been receiving for two years " a change driven by a federal executive order. A pharmacy mix-up meant his... Months before his first class at Carlow University, Lee, a 17-year-old in Pennsylvania, found himself without a provider. On a summer day, Lee sat waiting in a doctor's office, playing GamePigeon on his phone, telling family stories with his mom and deciding…...