Research presented by LRA, LT, and collaborators will address some of the most significant challenges in lupus, including reducing barriers to clinical trial participation, improving trial design and outcome assessment, evaluating molecular signatures associated with disease severity and treatment response,…
Scientists at La Jolla Institute for Immunology (LJI) and the University of Washington (UW) have discovered that patients with lupus have unusual mutations that may turn their bodies into battlegrounds. These mutations are widespread in immune cells called neutrophils. Other…
LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) and the University of Washington (UW) have discovered that patients with lupus have unusual mutations that may turn their bodies into battlegrounds. These mutations are widespread in immune cells…
Lupus affects around 1.5 million Americans, and nine out of ten people diagnosed with the disease are female. The root cause of lupus is unknown, and there is no cure. New research published in Nature shows that lupus patients have mutated…
Nature (2026) Cite this article Most of the cryptic splicing events yielding detectable neoantigen peptides occurred near the 3′ end of the open reading frame and therefore do not introduce premature stop codons that would result in NMD. Another set of peptides…
Patients with rheumatoid arthritis show faster remission and higher remission rates in recent decades than in the 1990s, yet those who reach remission face higher relapse rates. Remission Rates in Rheumatoid Arthritis Rise Since 1990s, but So Do Relapse Rates Patients with…
A histology showing the ankle joint of a mouse four days after receiving the new antibody treatment, V11 sFc. Newswise — Intravenous immunoglobulin (IVIG) therapy involves infusing patients with naturally occurring IgG antibodies to treat autoimmune conditions. With origins dating back to…
May 23, 2023, 08:53 ET People with lupus have played a key role in the development of the Lupus Nexus and will continue to be at the core of this effort through their participation in the Lupus Landmark Study. Their engagement will generate…
See all articles from Blog: ASTCT Update Growing evidence suggests they soon may have a similarly profound impact on autoimmune and other immunological disorders. To help clinicians navigate these developments, the American Society for Transplantation and Cellular Therapy (ASTCT) and…
The bioelectronic medicine trial will study how non-invasive stimulation might treat pain and fatigue in patients with lupus Dr. Cynthia Aranow is leading the vagus nerve stimulation lupus trial at the Feinstein Institutes for Medical Research (Credit: Feinstein Institutes) This…
CAR-T and other engineered cell therapies outside cancer care: lupus and other autoimmune diseases, new cell therapies, manufacturing and access.
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