Written by Steve Bryson, PhD | Oct. 23, 2026 Treatment with melatonin and pioglitazone, two approved drugs that act on metabolism, improved motor function and prolonged survival in a mouse model of spinal muscular atrophy (SMA), with melatonin having the greater impact on…
A domestic research team has developed an antibody candidate that could alleviate "cancer cachexia," a condition in which cancer patients lose weight and muscle strength. Animal tests confirmed effects in restoring appetite and reducing muscle and fat loss. A joint…
Scientists looking at why aging muscles weaken have found an unexpected twist. A decline in a little-known mitochondrial fat called cardiolipin appears to help drive the shift that changes muscle fibers with age, and that shift may function as a…
Published: Oct. 29, 2026 - 08:23:04 - KAIST develops antibody candidate to ease cancer cachexia - Grip strength improves 30% in mice; combination with anticancer drugs expected South Korean researchers have developed an antibody drug candidate that can prevent the appetite loss and muscle wasting caused by…
Researchers have found that declining cardiolipin levels may trigger a protective shift in ageing muscles, with potential implications for treating muscle loss. (A representative image) Scientists have discovered a hidden protective mechanism in ageing muscles that limits strength to shield…
Muscles naturally become weaker as we get older, but scientists have discovered that some of the changes associated with aging may actually help protect muscle cells from damage. New research reveals why aging muscles shift toward a different type of…
An experimental RNA therapy helped mice taking semaglutide lose more fat while preserving muscle, offering a possible way to improve weight-loss treatments. People who lose weight on a GLP-1 drug lose muscle along with the fat. For now, that has…
When you lose weight, you don’t just lose body fat. You lose muscle, too. Some muscle loss is normal, whether you lose weight through diet, exercise, weight loss medications, or surgery. But keeping as much muscle as possible matters for…
Physical capacity peaks by age 35 before steep losses begin, altering sarcopenia trajectories. Read more to explore clinical data. This site is intended for healthcare professionals Physical Capacity Decline Begins Decades Before Sarcopenia LONGITUDINAL data demonstrate that physical capacity decline begins…
Aging may not hit all at once, but a long-running Swedish study suggests the body begins to lose some of its edge far earlier than many people expect. Fitness, muscle endurance and physical performance generally start sliding around age 35, even…
Muscle loss with age and illness: sarcopenia, frailty and the treatments and habits that preserve muscle.
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