If improving your outlook on life really was as simple as "don't worry, be happy," then keeping your spirits up would be a piece of cake. Unfortunately, it's not so simple, as a multitude of factors beyond our control can…
Prostate cancer treatments often leave survivors with erectile dysfunction, for which inflatable penile prosthesis (IPP) surgery is a reliable solution. A new study reveals that men who had previously undergone androgen deprivation therapy (ADT) reported significantly lower satisfaction following IPP…
Scott Blanchard, PhD, co-corresponding author, St. Jude Department of Structural Biology The work built upon findings from a study the St. Jude team published in Nature in 2023, in which they used cryo-electron microscopy to determine the atomic structure of human…
A previously unknown mechanism helps cancer cells selectively produce proteins that drive tumor growth - such as KRAS - in common cancers, according to new research from The University of Texas MD Anderson Cancer Center. The findings reveal that targeting a specific…
(L to R) Qianqian Li, PhD; Dana Farmer, PhD; first author Justin Williams, PhD; corresponding author Martine Roussel, PhD, all of St. Jude Department of Tumor Cell Biology, and Jake Friske, PhD, St. Jude Graduate School of Biomedical Sciences Pediatric brain…
Complexity of pancreatic cancer reproduced in the laboratory The team used machine learning to categorize the newly grown organoids based on their morphologies in defined groups for further systematic analyses. "We identified different phenotypes within the two subtypes epithelial and…
The work built upon findings from a study the St. Jude team published in Nature in 2023, in which they used cryo-electron microscopy to determine the atomic structure of human ribosomes bound to eEF1A and compared mRNA decoding in human and bacterial…
In this Teach Me in 10, Dr. Uirá Souto Melo, molecular geneticist and CEO and co-founder of Lucid Genomics, explores the diagnostic potential of methylation analysis. Why Methylation Matters Now: Bridging Research and Diagnosis DNA sequence alone doesn’t tell the whole…
Dr. Manel Esteller and Dr. Verónica Dávalos, researchers at the Josep Carreras Leukaemia Research Institute, describe in a new article the impact of epigenetics on cancer treatment and how it has become a crucial tool to improve early detection, predict…
For almost 50 years, Fanconi anemia has been associated with leukemia. Not just among those who have the genetic disorder but among their family members, whose genes, they were told, made them highly susceptible to a variety of malignancies. But a…
How cancers start, grow and spread: tumour biology, genetics, lab and population studies, causes and major research findings.
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