For people living with depression, finding a treatment that actually works can sometimes take several attempts. Antidepressants may not bring enough relief, while switching medicines or combining treatments can involve more waiting, side effects and uncertainty. The findings, published in…
Amanita muscaria mushrooms have been used in Siberian shamanism for centuries, or perhaps as long as thousands of years. Some authors have speculated that the mushroom could be associated with other historical and cultural phenomena such as the mysterious magical…
Entropy has started dosing in Cohort 2 of its Phase II BED trial, testing a much shorter infusion regimen. Pic: Getty Images. Special Report: Dosing has started in Cohort 2 of Entropy Neurodynamics’ Phase II study of TRP-8803, with the first patient…
— News and commentary from the psychiatry world Actor Christopher Lloyd, 88, opened up about his struggles with addiction to cocaine, alcohol, and marijuana during the 1970s and 1980s. (USA Today) Health Secretary Robert F. Kennedy Jr. reportedly plans to bypass a candidate recommended…
Home › Drug & Medication News Research led by Mathieu Seynaeve, MD (King’s College London / AtaiBeckley) A clinical trial published in JAMA tested a drug called mebufotenin, also known as 5-MeO-DMT, whose psychedelic experience is unusually short. Earlier research cited in the…
Sitting at the base of a tree in Costa Rica, Dave L. cradled the trunk and wept. After decades in the Army, Dave had learned to bury his emotions and push through pain — a habit reinforced by the rigid ideas about…
Additionally, a 2023 systematic review of 10 psychedelic trials found that blinding, which keeps participants and staff unaware of who received the active drug versus a placebo, was either unsuccessful or never checked, likely because the drugs’ effects are so noticeable. Next,…
Psychedelic-therapy clinics such as this one need to be accessible to all.Credit: Cole Burston/AFP/Getty More than one billion people globally live with a mental-health condition. Collectively, these disorders are now the world’s leading cause of disability. Depression…
Despite this progress, a key challenge remains: how can the rapid and long-lasting therapeutic effects of psychedelics be preserved while minimizing acute hallucinogenic experiences and the practical demands of supervised dosing? Addressing this question will be crucial not only for…
Lynne Peeples is a science journalist in Seattle, Washington. The FDA refusal “stimulated a lot of thought and conversation”, says Rachel Yehuda, a neuroscientist at Icahn School of Medicine at Mount Sinai in New York City. “But it didn’t make…
Psilocybin, MDMA, ketamine and ibogaine as treatments: clinical trials, approvals, state programmes and clinics.
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